Osteochondral Lesion of the Talus (OLT)

(aka Talar OCDs or Talar OCLs)

Edited by Kenneth Hunt, MD


An osteochondral lesion of the talus (OLT) is an area of abnormal, damaged cartilage and bone on the top of the talus bone (the lower bone of the ankle joint).  This condition is also known as either osteochondritis dissecans (OCD) of the talus or as a talar osteochondral lesion (OCL).  It is often associated with a traumatic injury, such as a severe ankle sprain. However, it can also occur from chronic overload due to malalignment or instability of the ankle joint.OCLs most commonly occur in two areas of the talus (Figure 1A and 1B):
  1. The inside and top part of the lower bone of the ankle (the medial talar dome) or
  2. The outside and top part of the lower bone of the ankle (the antero-lateral talar dome).

Figure 1: MRI of Medial (Inside) Talar OLT

Figure 1B: MRI of Lateral (Outside) Talar OCL

Clinical Presentation

Many patients with talar OLTs are asymptomatic. OLTs can be serendipitously identified on an MRI ordered to assess another problem. However, if the lesion is large enough, or the overlying cartilage is displaced, talar OLTs can be quite symptomatic. Patients with this condition often complain of localized ankle pain, as well as discomfort on either the inside (medial talar OLT) or outside (anterolateral talar OLT) of the ankle. The pain is often worse with activities, particularly running, walking and jumping. They may also complain of mechanical symptoms, such as clicking and popping sounds associated with the osteochondral lesion, if there is a loose fragment of cartilage and/or bone associated with the OLT. Increased ankle pain with activity is also common. 

OLTs on the top outside part of the talus (Antero-lateral lesions) usually have a history of a traumatic injury with a twisting component, such as an ankle sprain. Whereas, the OLTs on the inside part of the top of the talus (medial talar osteochondral lesions) are more commonly associated with chronic overload of the medial aspect of the ankle, such as would occur in a patient with a higher arched foot (subtle cavus foot). Physical exam usually reveals some swelling and localized pain along the front of the ankle (ankle joint line).

Imaging Studies

Plain x-rays can be used to help diagnose an osteochondral lesion. Areas of decreased density (i.e., darker areas) seen on the plain x-rays (Figure 2) can be indicative of this condition, although it is not uncommon for the plain x-rays to be read as normal. The gold standard for diagnosis of talar OLTs is an MRI of the ankle (Figure 3A and 3B).
Figure 2: Medial Talar OLT on plain X-Rays

Figure 3A: MRI Lateral (side) view of Talar OLT

Figure 3B: MRI Anteroposterior (view from front) of Talar OLT


Non-Operative Treatment

Non-operative treatment can be successful for non-displaced talar OLTs, especially if the condition is recognized and treated relatively early, and the lesion is relatively small. Younger patients, particularly growing children or adolescents, have a much better chance of healing an OLT compared to adults. There are several non-operative management options for the treatment of osteochondral lesions, including:
  • Cast immobilization: If the OLT occurs following an acute injury, initial immobilization in a cast for 4-6 weeks can help reduce stress on the OLT and allow healing.  This treatment approach can be initially attempted in non-displaced OLTs.
  • Physical therapy: working on strengthening the muscles around the ankle, range of motion of the ankle, and balancing (proprioception)
  • Protective braces (ex. Ankle Lacer) to decrease stress can also be utilized.

In younger patients, this condition has the potential to heal, making it possible to treat acute non-displaced talar OCLs with immobilization in a cast or CAM walker.

Operative Treatment

Surgical treatment is indicated for displaced talar OLTs or lesions that have not improved with appropriate non-operative management. Surgical treatment of talar OLTs includes:
  • Arthroscopic debridement (cleaning out) and microfracture of the talar OLT. This is the standard operative treatment and leads to good or excellent results in 75-80% of patients with typical talar OCLs (less than 15mm²)
  • Osteochondral Autologous Autograft Transfer (OATs Procedure) An OATs-type procedure is reserved for patients who have been treated with arthroscopic cleaning out (debridement) and microfracture and are still not doing well, or patients that have a very large (>20mm²) talar OLT. This procedure may also be called a mosaicplasty. The theoretical advantage of this procedure is that it replaces the damaged cartilage with real cartilage from the patient, taken from somewhere else (ex. the knee joint). The main disadvantage of this procedure is the prolonged recovery time and increased complication rate, compared to arthroscopic debridement. The graft is usually taken (harvested) from the patient’s knee on the same leg, from an area of that joint that does not bear any load. Patients can develop knee pain after this procedure.
  • Osteochondral Allograft Transfer (i.e., Cadaver): A bone and cartilage plug may also be obtained from a cadaver and transplanted into the OLT. This prevents the need from harvesting bone and cartilage from another part of the body (ex. knee). However, blood tests must be performed to ensure that the donor specimen is free of diseases (ex. HIV, Hep B, etc.), which this takes time. During this time, many of the cartilage cells in the donor graft die, which may affect the integrity of the graft after it has been inserted. Osteochondral allografts (Cadaver grafts) have been used to treat large talar lesions with some success. However, the larger the graft, the more likely it seems that it will collapse as a new blood supply is established into the graft after transplantation. This is one of the reasons that complete ankle replacement using all cadaver (donor) bone and cartilage has not done as well as orthopaedic surgeons had initially hoped.
  • Autologous chondrocyte transplantation (ACI): There has been an attempt to harvest a patient's own healthy cartilage, grow the cells in a lab, and then reimplant these cells back into the area where the cartilage has been lost. Unfortunately this approach has not yet met with the type of clinical success that had been hoped for, and is not currently broadly available. One of the barriers to this technique that has been difficult to overcome is that the cartilage cells themselves represent only a tiny portion of the "normal cartilage".  A much greater part is the surrounding "matrix", which is highly organized in normal cartilage and which has not yet been reproduced in the laboratory. The “subchondral” bone that supports cartilage is also important to clinical success. Laboratory and clinical work continue in this area.

Other Procedures

Any other significant pathology that exists may also need to be addressed at the time of surgery. This may include:

Edited December 28, 2016

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